Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and Titanium amplicon pyrosequencing and metagenomic approaches

October 30th, 2009

Wolcott RD et al. – The polymicrobial nature of VLU and previous research on diabetic foot ulcers and surgical site infections suggest that the future of therapy for such wounds lies in the core of the logical and proven multiple concurrent strategy approach, which has been termed “biofilm–based wound care” and the use of individualized therapeutics rather than in a single treatment modality. read more

Influenza A(H1N1)v pandemic in the dialysis population: first wave results from an international survey

October 30th, 2009

Marcelli D et al. – End–stage renal disease patients should be included in first ranks of the priority list for the influenza A(H1N1)v vaccine, as already advocated by some healthcare authorities.
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Antimicrobial Susceptibility Testing: A Primer for Clinicians

October 29th, 2009

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Epidemiology and Impact of Imipenem Resistance in Acinetobacter baumannii

October 29th, 2009

Lautenbach E et al. – Many A. baumannii isolates exhibit imipenem resistance, which is strongly associated with prior use of carbapenems. Given the high mortality rate associated with A. baumannii infection or colonization, interventions to curb further emergence of cases of IRAB infection and strategies to optimize therapy are needed.
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Hyperbaric oxygen therapy as an anti-infective agent

October 26th, 2009

Cimsit M et al. – HBOT is used as either a primary or adjunctive treatment in the management of infections such as gas gangrene, necrotizing fasciitis, diabetic foot infections, refractory osteomyelitis, neurosurgical infections and fungal infections. HBOT acts as a bactericidal/bacteriostatic agent against anerobic bacteria by increasing the formation of free oxygen radicals. HBOT restores the bacterial–killing capacity of leukocytes in hypoxic wounds by increasing tissue oxygen tensions. read more

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