SpectraTM MRSA, A New Chromogenic Agar Medium to Screen for Methicillin-Resistant Staphylococcus aureus

December 1st, 2009

SpectraTM MRSA was able to rapidly identify and differentiate methicillin–resistant S. aureus from methicillin–susceptible S. aureus based on the utilization of chromogens that result in denim blue colonies, thus eliminating the need for biochemical analysis and antimicrobial susceptibility testing. Extending the incubation beyond 24 h did not significantly improve the recovery of MRSA and resulted in decreased specificity read more

Treatment of Clostridium difficile infection in older adults

December 1st, 2009

The approach to treatment of Clostridium difficile infection (CDI) in older adults presents unique challenges, and selection of an effective treatment regimen is often not straightforward. read more

Multidrug-Resistant Gram-Negative Bacteria at a Long-Term Care Facility: Assessment of Residents, Healthcare Workers, and Inanimate Surfaces

December 1st, 2009

The prevalence of MDR gram-negative bacteria is high among LTCF residents and exceeds that of vancomycin–resistant enterococci and methicillin–resistant S. aureus. Common areas in LTCFs may provide a unique opportunity for person–to–person transmission of MDR gram–negative bacteria.
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Principles of antibiotic therapy

December 1st, 2009

The aminoglycosides and fluoroquinolones exhibit ‘concentration-dependent killing’ and so higher doses are associated with greater efficacy. β-Lactams, erythromycin, clindamycin, and linezolid demonstrate ‘time-dependent killing’ and therefore duration above minimum inhibitory concentration is more important. read more

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