Growth in glucose-based medium and exposure to subinhibitory concentrations of imipenem induce biofilm formation in a multidrug-resistant clinical isolate of Acinetobacter baumannii

January 13th, 2010

Nucleo E et al. – The results indicate that exposure to subinhibitory concentrations of imipenem can stimulate biofilm formation and induce iron uptake in a pathogenic strain of A. baumannii, with potential implications on antibiotic susceptibility and ability to persist in the human host. read more

Recent Microbiological Shifts in Perianal Bacterial Dermatitis: Staphylococcus aureus Predominance

January 13th, 2010

Silverberg NB et al. – Staphylococcus aureus has become the leading cause of anal bacterial infection in the setting of skin involvement; therefore, antibacterial therapy for anal and buttock bacterial infections should be tailored accordingly. read more

Imipenem-resistant Pseudomonas aeruginosa gastrointestinal carriage among hospitalized patients: risk factors and resistance mechanisms

January 5th, 2010

Lepelletier D et al. – The authors confirmed that IMP use selects for IRPA in the gut flora. Cross–transmission, however, was frequently observed in intensive care units. Combining epidemiologic approach and molecular analysis is a powerful tool to delineate mechanisms of emerging resistance.
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The Relationship Between Time to Surgical Débridement and Incidence of Infection After Open High-Energy Lower Extremity Trauma

January 5th, 2010

Pollak AN et al. – The time from the injury to operative débridement is not a significant independent predictor of the risk of infection. Timely admission to a definitive trauma treatment center has a significant beneficial influence on the incidence of infection after open high–energy lower extremity trauma. read more

Community-Acquired Methicillin-Resistant Staphylococcus aureus in Surgically Treated Hand Infections

January 5th, 2010

Imahara SD et al. – The proportion of surgically treated hand infections due to CA–MRSA has increased during the last decade. Intravenous drug use was the only independent risk factor for CA–MRSA infections treated in the operating room at the institution. read more

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