February 17th, 2010
Kypraios T et al. – Screening consistently detected >80% of colonized–patient–days. Estimates of the effectiveness of barrier precautions showed considerable uncertainty, but in all units except burns/general surgery and one cardiac surgery ICU, the best estimates were consistent with reductions in transmission associated with barrier precautions. read more
February 17th, 2010
Jakobsen MR et al. – The authors found the prevalence of TDR in recently infected ART-naive patients to be higher than that estimated by ViroSeq genotyping alone. Follow-up of patients after treatment initiation showed a trend toward there being more clinical complications for patients carrying TDR, although a significant effect on treatment outcome could not be demonstrated. Therefore, the clinical relevance of low-abundance resistant quasispecies in early infection is still in question. read more
February 15th, 2010
Wadl M et al. – The increase of MDR in A. baumannii isolates from 2002 to 2006 in four hospitals suggests that clinicians in Germany may expect a rising proportion of MDR in A. baumannii isolates among inpatients. The antimicrobial susceptibility testing of A. baumannii isolates against recommended drugs, combined with in–house antimicrobial resistance surveillance, is needed to ensure appropriate treatment. read more
February 15th, 2010
Chemaly RF et al. – Several clinical and postoperative factors were associated with increased risk of MRSA SSI in cancer patients, but antibiotic use before surgery (especially quinolones) and progressive cancer were the only independent predictors. read more
February 15th, 2010
Rad EG et al. – A limited number of community acquired MRSA strains were detected. These included ST–188/t189, ST–1/t127 and ST–7/t091. PVL was detected in all ST–1 and ST–188 strains and in 0.7 percent of the ST239 isolates. The majority of the isolates carried agr I, except that ST–1 strains were agr III positive. Virulence genes seg and sei were seen only among ST22 isolates. Current results revealed the predominance of the ST–239–SCCmec–III/IIIA and the penetration of ST–22 with different virulence gene profiles. The Malaysian emergence of novel clones of known epidemic and pathogenic potential should be taken seriously. read more
