Importance of Colonization Site in the Current Epidemic of Staphylococcal Skin Abscesses

March 12th, 2010

Faden H et al. – Skin and soft–tissue abscesses in the current epidemic of community–associated staphylococcal disease are strongly associated with rectal colonization by PFT USA300. Nasal colonization in children does not seem to be a risk factor. read more

Prevalence, Resistance Mechanisms, and Susceptibility of Multidrug-Resistant Bloodstream Isolates of Pseudomonas aeruginosa

March 12th, 2010

Tam VH et al. – All available isolates were susceptible to polymyxin B, and only one isolate was nonsusceptible to colistin, but all isolates were nonsusceptible to doripenem. Understanding and continuous monitoring of the prevalence and resistance mechanisms of MDR P. aeruginosa would enable us to formulate rational treatment strategies to combat nosocomial infections. read more

Poor Functional Status Is an Independent Predictor of Surgical Site Infections Due to Methicillin-Resistant Staphylococcus aureus in Older Adults

March 2nd, 2010

Chen T–Y et al. – Poor functional status (requiring assistance in >=3 activities of daily living (ADLs)) was specifically associated with MRSA SSI. Functional status is an objective, readily available variable that can be used to stratify patients at risk for MRSA SSI.
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Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost

March 2nd, 2010

Lipsky BA et al. – Among diabetic patients hospitalised with skin and soft tissue infections (SSTIs) from 2003 to 2007, only methicillin–resistant Staphylococcus aureus (MRSA) increased in prevalence. Patients with non–foot (vs foot) infections were more severely ill. Independent risk factors for increased mortality rates, length of stay and costs included more severe illness, transfer from another hospital and wound cultures with Pseudomonas or other gram–negatives. read more

Major differences exist in frequencies of virulence factors and multidrug resistance between community and nosocomial Escherichia coli bloodstream isolates

March 2nd, 2010

Cooke NM et al. – The community, healthcare–associated or nosocomial origin of E. coli bacteremia determines isolates’ virulence capacity better than phylogenetic group. This study provides new insights into the relationships between pathogenesis and epidemiology of E. coli bacteremia. read more

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