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Jump RLP et al. – To determine whether a multihospital Clostridium difficile outbreak was associated with epidemic strains and whether use of particular fluoroquinolones was associated with increased infection rates, the authors cultured feces from C. difficile–infected patients. Use of fluoroquionolones with enhanced antianaerobic activity was not associated with increased infection rates. read more
Stevens AM et al. – Skin infections were more likely to develop in MRSA carriers than in methicillin–susceptible S. aureus carriers or noncarriers of S. aureus during the first follow–up year, but not in subsequent years. Repeated skin infections were more common among MRSA carriers. In an area where PVL–containing MRSA is prevalent, skin infection risk was increased among MRSA nasal carriers compared with methicillin–susceptible S. aureus carriers and noncarriers, but risk differential diminished over time. read more
De Serres G et al. – Human challenge studies with seasonal influenza have shown that virus shedding after day 7 is rare, but clinical studies have shown that shedding may persist beyond that period in some populations, such as elderly persons, immunocompromised patients, and children. In a study among hospitalized persons infected with seasonal influenza A viruses, 54% remained positive by PCR beyond 7 days after symptom onset, and 29% were positive by cell culture. read more
Schaefer MK et al. – Code combinations were better at revealing CO–MRSA infections than HO–MRSA infections. These limitations could compromise the validity of ICD–9–CM codes for interfacility comparisons and for reporting of healthcare–associated MRSA infections.
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Achkar JM et al. – Despite its high incidence and clinical relevance, genitourinary candidiasis is understudied, and therefore, important questions about pathogenesis and treatment guidelines remain to be resolved. In this review, the authors summarize the current knowledge about genitourinary candidiasis. read more
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