Determinants of carriage of resistant Staphylococcus aureus among S. aureus carriers in the Indonesian population inside and outside hospitals

July 30th, 2010

Lestari ES et al. – Antibiotic policies including proper diagnosis, treatment and drug delivery process should be made by healthcare providers in Indonesia to help limit the emergence of antibiotic resistance. read more

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus {alpha}-hemolysin-mediated cellular injury

July 30th, 2010

Wilke GA et al. – These data implicate ADAM10 as the probable high–affinity toxin receptor. Upon Hla binding, ADAM10 relocalizes to caveolin 1–enriched lipid rafts that serve as a platform for the clustering of signaling molecules. It is demonstrated that the Hla–ADAM10 complex initiates intracellular signaling events that culminate in the disruption of focal adhesions.
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SBN: Dr. White, DPM

July 29th, 2010

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Emergence and Dissemination of Extended-Spectrum beta-Lactamase–Producing Escherichia coli in the Community: Lessons from the Study of a Remote and Controlled Population

July 26th, 2010

Woerther PL et al. – In this population, the frequency of ESBL increased with time because of the appearance of CTX–M ESBL, mimicking what occurs in the developed world. This resulted from the probable repeated introduction of new strains and plasmids and from interindividual dissemination. During the same period, antibiotic use substantially increased.
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Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital

July 21st, 2010

Multidrug resistant Acinetobacter baumannii, (MRAB) is an important cause of hospital acquired infection. The purpose of this study is to determine the risk factors for MRAB in a city hospital patient population read more

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