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Butler MS et al. – The emergence of multi–drug–resistant bacteria and the lack of new antibiotics in the antibiotic drug development pipeline, especially those with new modes of action, is a major health concern. read more
Stephen P. Hawsera, , , Samuel K. Bouchillonb, Daryl J. Hobanb, Michael Dowzickyc and Tim Babinchakca
aIHMA Europe Sàrl, 4 Route de la Corniche, 1066 Epalinges, Switzerland
b International Health Management Associates, Schaumburg, IL, USA
c Pfizer, Inc., Collegeville, PA, USA
Received 30 September 2010; accepted 28 October 2010. Available online 15 January 2011. read more
Oake N et al. – Hospital–acquired Clostridium difficile infection was independently associated with an increased risk of in–hospital death. Across all baseline risk strata, for every 10 patients acquiring the infection, 1 person died. read more
Hass L – Nosocomial infections are increasingly multidrug resistant and at times more virulent. As such, they pose real threats to patients and clinicians. In this essay the author discusses his own methacillin–resistant staphylococcus infection and how it has affected his work in the hospital. In so doing, he reflects on the value of touch in the doctor–patient relationship. In particular, he discusses how gloves serve as a barrier to infection but also create a small distance between the doctors and their patients. The implications of contact precautions must be considered as we reflect on balancing patient–centered care with infection control. read more
Clements ACA et al. – This framework first requires identification of potential vehicles of introduction, including international transfers of hospital patients, international tourism and migration, and trade in livestock, associated commodities, and foodstuffs. It then calls for assessment of the risks of pathogen release, of exposure of individuals if release happens, and of resulting outbreaks. Health departments in countries unaffected by outbreaks should assess the risk of introduction or reintroduction of C difficile PCR ribotype 027 using a structured risk–assessment approach. read more
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