June 1st, 2010
Mellerio JE – A balance exists between a wound’s bacterial load and the host defenses, such that there is a spectrum from simple contamination, through colonization, critical colonization, to overt infection. The increased bioburden in critically colonized or infected wounds impairs healing and therefore recognition of these situations, and appropriate measures to promote a healing environment, are fundamental to the care of EB wounds. read more
June 1st, 2010
Mascitti KB et al. – Among pediatric and adult providers, 70% preferred trimethoprim–sulfamethoxazole for directed treatment of community–associated methicillin–resistant Staphylcoccus aureus skin and soft–tissue infections, although a higher proportion of pediatric compared with adult providers favored clindamycin. For recurrent infections, 88% of providers employed at least 1 topical decolonization strategy. read more
May 26th, 2010
Rolston K et al. – Although all S aureus isolates were susceptible to vancomycin, 63% of methicillin–susceptible isolates and 82% of methicillin–resistant isolates had MIC values of > 1.0 (microgram)/mL for this agent, indicating the need for alternative therapeutic agents. The organisms were susceptible to trimethoprim/sulfamethoxazole, rifampin, linezolid, daptomycin, and tigecycline.
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May 12th, 2010
Honda H et al. – ICU patients colonized with S. aureus were at greater risk of developing a S. aureus infection in the ICU. Even after adjusting for patient–specific risk factors, MRSA–colonized patients were more likely to develop S. aureus infection, compared with MSSA–colonized or noncolonized patients. read more
May 11th, 2010
Burkitt KH et al. – In this multicenter study of VA employees, implementation of a MRSA quality improvement initiative was associated with temporal improvements in knowledge and perceptions regarding MRSA prevention.
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