A professional news service dedicated to publishing up-to date-information regarding infection causing agents, anti-infective products and therapies.
De Kraker MEA et al. – Antimicrobial resistance is threatening the successful management of nosocomial infections worldwide. Despite the therapeutic limitations imposed by methicillin–resistant Staphylococcus aureus (MRSA), its clinical impact is still debated. read more
Jolivet–Gougeon A et al. – Antibiotics can also act as indirect promoters of antibiotic resistance by inducing the SOS system and certain error–prone DNA polymerases. These alterations have clinical consequences in that efficacious treatment of bacterial infections requires high doses of antibiotics and/or a combination of different classes of antimicrobial agents. There are currently few new drugs with low endogenous resistance potential, and the development of such drugs merits further research. read more
Huang JT et al. – Chronic use of dilute bleach baths with intermittent intranasal application of mupirocin ointment decreased the clinical severity of atopic dermatitis in patients with clinical signs of secondary bacterial infections. Patients with atopic dermatitis do not seem to have increased susceptibility to infection or colonization with resistant strains of S aureus. read more
Buchan BW et al. – While the development of new antibiotics such as tigecycline holds some promise for treating these resistant strains, the best interventional strategy is to prevent nosocomial spread through the use of screening, contact isolation and good hand hygiene practices. read more
Zubair M et al. – Poor glycemic control in 68.6% patients, duration of infection >1 month and ulcer size> 4cm2 were independently associated with risk of Multidrug resistance organisms infection read more
