Management of Skin and Soft Tissue Infections in Community Practice Before and After Implementing a ‘Best Practice’ Approach: An Iowa Research Network (IRENE) Intervention Study
Daly JM et al. – The Centers for Disease Control and Prevention (CDC) algorithm was feasible for offices to use. Following a discussion of skin and soft tissue infections (SSTIs) management in the outpatient setting, use of methicillin–resistant Staphylococcus aureus (MRSA) coverage increased both initially and overall. Thus, involving clinicians in a discussion about guidelines rather than simply providing guidelines or a didactic session may be a useful way to change physician practices.
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Clinical and Molecular Characteristics of Invasive and Noninvasive Skin and Soft-Tissue Infections Caused by Group A Streptococcus
Lin JN et al. – Dendrogram analysis showed a unique pulsed–field gel electrophoresis–SmaI pattern of emm106 that was particularly prone to cause invasive skin and soft–tissue infections. This study suggests that emm106 may be an emerging group A Streptococcus strain that causes invasive skin and soft–tissue infections. Further surveillance study to understand the significance of this invasive strain is critical read more
Risk Factors and Mortality of Health Care-Associated and Community Acquired Staphylococcus aureus Bacteremia
Bassetti M et al. – Logistic–regression analysis identified 3 variables as independent predictors of mortality: presentation with septic shock, infection due to methicillin–resistant S. aureus (MRSA), and initial inadequate antimicrobial treatment. More than one half of patients with Staphylococcus aureus bacteremia has MRSA strains and presentation with septic shock, and inappropriate empirical therapy was associated with increased mortality. read more
Characteristics of Invasive Staphylococcus aureus in United Kingdom Neonatal Units
Vergnano S et al. – Staphylococcus aureus (SA) is the second most common pathogen causing late–onset neonatal infections in this neonatal network. Infants who weigh <1500 g in intensive care settings are the most vulnerable group. Clinical signs are not sufficiently distinctive to allow targeted therapy, suggesting that an antistaphylococcal agent should be part of empiric therapy for late–onset sepsis in premature infants. read more
Share Staphylococcus aureus Screening and Decolonization and Orthopaedic Surgical Site Infection- A Review of Literature and Single Institution Experience
Hutzler LH et al. – Evidence shows that nasal colonization is a risk factor for surgical site infections and there is mounting evidence that decolonization is a potential strategy for decreasing infection rates in the orthopaedic population. Screening and decolonization of S. aureus infections may reduce the need for revision surgeries, additional hospitalizations, use of intravenous antibiotics and decrease the incidence of recurrent infections. Studies have demonstrated high potential cost savings associated with screening and decolonizing patients prior to high risk orthopaedic procedures read more
