Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital

July 21st, 2010

Multidrug resistant Acinetobacter baumannii, (MRAB) is an important cause of hospital acquired infection. The purpose of this study is to determine the risk factors for MRAB in a city hospital patient population read more

Epidemic meticillin-resistant Staphylococcus aureus (EMRSA-15) variants detected in healthy and diseased individuals in India

July 8th, 2010

Nadig S et al. – All isolates were positive for Panton–Valentine leukocidin and toxic shock syndrome toxin, which is a cause for concern. In addition to soft–tissue infections, the EMRSA–15 isolates from patients were also responsible for meningitis and brain abscesses, which is quite rare.
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Predicting Bacteremia among Patients Hospitalized for Skin and Skin‐Structure Infections: Derivation and Validation of a Risk Score

July 8th, 2010

Lipsky BA et al. – Using data available at hospital admission, the authors developed a risk score that differentiated SSSI patients at low risk for bacteremia from patients at high risk. This score may help clinicians identify patients who require more intensive monitoring or antimicrobial regimens appropriate for treating bacteremia. read more

Relationship of Vancomycin MIC to Mortality in Patients with Methicillin-Resistant Staphylococcus aureus Hospital-Acquired, Ventilator-Associated and Healthcare-Associated Pneumonia

June 28th, 2010

Haque NZ et al. – Mortality in patients with MRSA HAP, VAP, and HCAP increases as a function of the vancomycin MIC even for strains with MIC values within the susceptible range. Evaluation of vancomycin MICs should be contemplated at the institutional level and for individual cases of MRSA pneumonia. The use of vancomycin therapy in patients with MRSA pneumonia caused by isolates with MICs between 1 and 2 (mu)g/mL should be undertaken with caution and alternative therapies should be considered. read more

The Value of Infectious Diseases Consultation in Staphylococcus aureus Bacteremia

June 28th, 2010

Honda H et al. – Only one third of patients with S. aureus bacteremia in this cohort had an infectious diseases specialist consultation. Infectious diseases consultation was independently associated with a reduction in 28–day mortality. Routine infectious diseases consultation should be considered for patients with S. aureus bacteremia, especially those with greater severity of illness or multiple comorbidities. read more

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