Incidence of and Risk Factors for Community-associated Clostridium difficile Infection: a nested case-control study
Kuntz JL et al. – The authors study documented that the epidemiology of Clostridium difficile infection is changing, with community–associated Clostridium difficile occurring in populations not traditionally considered “high–risk” for the disease. Clinicians should consider this diagnosis and obtain appropriate diagnostic testing for outpatients with persistent or severe diarrhea who have even remote antimicrobial exposure. read more
Necrotizing fasciitis: review of 82 cases in South Auckland
Nisbet M et al. – Necrotizing fasciitis (NF) remains an important disease in the community with significant morbidity and mortality. Pacific Islanders were disproportionately represented. Early diagnosis of NF can be difficult and requires a high index of suspicion in all patients presenting with cellulitis or unexplained sepsis. Congestive heart failure and gout are independent predictors of mortality and patients with these conditions and sepsis need early assessment with more aggressive hospital triaging. read more
Epidemiological and clinico-mycological profile of fungal wound infection from largest burn centre in Asia
Capoor MR et al. – This study depicted that fungal invasion is associated with a high mortality, burn size 30–60% and high incidence of inhalational injury. Fungal invasion was detected on an average of 14 days after injury. Association of use of four classes of drugs – aminoglycosides, imipenem, vancomycin and third generation cephalosporins and use of total parenteral nutrition was observed.
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Pulmonary Infections and Community Associated Methicillin Resistant Staphylococcus Aureus: A Dangerous Mix?
Shilo N et al. – It still is not clear whether community–associated methicillin–resistant Staphylococcus aureus (CA–MRSA) is a marker for worsening disease or whether it actually is a cause of disease progression in cystic fibrosis. More longitudinal data is needed to understand how MRSA colonization impacts the course of disease in cystic fibrosis. read more
Prediction of Infection Due to Antibiotic-Resistant Bacteria by Select Risk Factors for Health Care–Associated Pneumonia
Shorr AF et al. – Although resistance is common in HCAP, not all component criteria for HCAP convey similar risk. Simple scoring tools may facilitate more accurate identification of persons with pneumonia caused by resistant pathogens.
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